CERTAINTY at the 8th European CAR T-Cell Meeting

From 12–14 February 2026, the EBMT–EHA 8th European CAR T-Cell Meeting took place in Palma de Mallorca, bringing together leading experts in cellular immunotherapies for cutting-edge science, clinical insights, and discussion.

CERTAINTY partners actively contributed to the scientific programme with three talks and three posters, showcasing progress in personalised CAR T cell therapy for multiple myeloma and highlighting the project’s integrated approach to data, biology, and digital innovation.

Oral Presentations

CERTAINTY contributions featured prominently in the main programme:

A Longitudinal Single-cell Atlas to Predict Outcome and Toxicity after BCMA-directed CAR T Cell Therapy in Multiple Myeloma

Michael Rade (Leipzig, Germany)

CERTAINTY Project and Future Outlook

Kristin Reiche (Leipzig, Germany)

Panel discussion, Q&A, and closing remarks

Kristin Reiche (Leipzig, Germany)

Multi-omics single cell, 3D imaging and resistance in niche

Zsolt Sebestyen (UMC Utrecht)

These presentations reflected CERTAINTY’s ambition to integrate longitudinal single-cell data, mechanistic modelling, and digital tools to improve outcome prediction and therapy optimisation in multiple myeloma.

Poster Contributions

CERTAINTY research was also represented through three poster presentations:

CERTOMICS: Trusted Single-cell Multiomics Pipeline for High-resolution Profiling of Adoptive Cellular Immunotherapies

Christina Kuhn (Leipzig, Germany)

Personalised Multilevel Modelling to Unveil Mechanisms behind Engineered T Cell Therapy Response in Multiple Myeloma

Sophia Orozco-Ruiz (Paris, France)

The Cost Savings Potentials of Virtual Twins for Personalised CAR T Cell Therapy in Multiple Myeloma

Marija Radic (Leipzig, Germany)

Together, these contributions highlighted the strength of CERTAINTY’s multidisciplinary approach, spanning a trusted single-cell multi-omics pipeline, mechanistic modelling, health economic analysis, and Virtual Twin development.

Integrating Data, Biology, and Digital Innovation

From longitudinal single-cell atlases predicting toxicity, to multi-level computational modelling, to health economic analyses of Virtual Twins, discussions at the CAR T-Cell Meeting underscored the importance of integrating high-resolution biological data with robust digital infrastructure.

The meeting provided an excellent platform to exchange insights with the wider CAR T cell community, engage in scientific debate, and strengthen collaboration across clinical, computational, and translational research domains.

Moments from Palma

Take a look at the photos below for impressions from the meeting.

We would like to thank everyone who joined the sessions, visited the posters, and contributed to the inspiring discussions throughout the meeting.